Critical Needs in Advancing Shigella Vaccines for Global Health
MacLennan CA., Talaat KR., Kaminski RW., Cohen D., Riddle MS., Giersing BK.
Advancing new O-antigen-based Shigella vaccines is critically dependent on development of an international standard serum and harmonized ELISA, demonstration of field efficacy in young children in low- and middle-income countries, and early engagement with regulators and policy makers.